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Faculty Directory » Sean Rollins


Office Hours:

Semester: Fall 2019
Tuesday and Thursday 8:00am - 9:15am in SCI 110

Office Information:

Room Number: SCI 237
Phone: (978) 665-3915

Courses Taught:

General Microbiology (BIOL 3900)
Survey of Microorganisms
General Biology I (BIOL 1800)


Post-Doctoral Fellowship, Harvard Institute of Proteomics, Harvard Medical School (Biological Chemistry and Molecular Pharmacology)
Post-Doctoral Fellowship, Massachusetts General Hospital, Harvard Medical School (Infectious Diseases)
Ph.D., Ohio State University (Microbiology)
B.S., Rensselaer Polytechnic Institute (Biology)

Research Interests:

My primary research interests are with host/pathogen interactions and gene regulation of Bacillus anthracis, Vibrio cholerae and Salmonella species, particularly as it relates to vaccine, diagnostic and therapeutic development.

Current Projects:

Utilizing proteomic techniques to study immune responses during anthrax, cholera and typhoid.

Gene expression analysis of a large family of Bacillus anthracis genes containing transcriptional elements suggesting induced expression in response to specific amino acid limitation.

Representative Publications:

Festa, F, S.M. Rollins, K. Vattem, M. Hathaway, P. Lorenz, E.A. Mendoza, X. Yu, J. Qiu, G. Kilmer, P. Jensen, B. Webb, E.T. Ryan and J. Labaer. "In Press. Robust microarray production of freshly expressed proteins in a human milieu." Proteomics Clinical Appl.

Rollins, S.M. and R. Schuch. 2010. "Crowd control: Bacillus anthracis and quorum sensing." Virulence 1:2:57-59.

Rollins, S.M., A. Peppercorn, J.S. Young, M. Drysdale, A. Baresch, M.V. Bikowski, D. Ashford, C.P. Quinn, J.D. Hillman, M. Handfield, C.R. Lyons, T.M. Koehler, S.B. Calderwood, E.T. Ryan. 2008. "Application of In Vivo Induced Antigen Technology (IVIAT) to Bacillus anthracis." PLOS ONE 3:e1824.

Rollins, S.M., A. Peppercorn, L. Hang, J.D. Hillman, S.B. Calderwood, M. Handfield and E.T. Ryan. 2005. "In vivo induced antigen technology (IVIAT)." Cell Microbiol. 7:1-9.

Rollins, S.E., S.M. Rollins and E.T. Ryan. 2003. "Yersinia pestis and the plague." Am. J. Clinical Pathol. 119:(Supplement1) S1-S8.

Rollins, S.M., F.J. Grundy, and T.M. Henkin. 1997. "Analysis of cis-acting sequence and structural elements required for antitermination of the Bacillus subtilis tyrS gene." Mol. Microbiol. 25:411-421.

Grundy, F.J., S.M. Rollins, and T.M. Henkin. 1994. "Interaction between the acceptor end of tRNA and the T box stimulates antitermination in the Bacillus subtilis tyrS gene: a new role for the discriminator base." J. Bacteriol. 176:4518-4526.

Denholm, E.M., and S.M. Rollins. 1993. "Expression and secretion of transforming growth factor-beta by bleomycin-stimulated rat alveolar macrophages." Am. J. Physiol. 264(1 Pt 1):L36-L42.

Denholm, E.M., and S.M. Rollins. 1993. "Alveolar macrophage secretion of a 92-kDa gelatinase in response to bleomycin." Am. J. Physiol. 265(6 Pt 1):L581-L585.

Professional Affiliations:

MGH - Massachusetts General Hospital (Assistant of Microbiology)
MCPHS - Massachusetts College of Pharmacy and Health Sciences (Adjunct Instructor of Biology)
ASM - American Society of Microbiology