Sean Rollins, Ph.D., Biology and Chemistry | Fitchburg State University
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Faculty Directory » Sean Rollins

Biology/Chemistry

Office Hours:

Semester: Spring 2020
Tuesday and Thursday 8:00am - 9:20am in SCI 110

Office Information:

Room Number: Antonucci Science Complex 237
Phone: 978.665.3915
Email: srollins@fitchburgstate.edu

Courses Taught:

General Microbiology (BIOL 3900)
Survey of Microorganisms
General Biology I (BIOL 1800)

Education:

Post-Doctoral Fellowship, Harvard Institute of Proteomics, Harvard Medical School (Biological Chemistry and Molecular Pharmacology)
Post-Doctoral Fellowship, Massachusetts General Hospital, Harvard Medical School (Infectious Diseases)
Ph.D., Ohio State University (Microbiology)
B.S., Rensselaer Polytechnic Institute (Biology)

Research Interests:

My primary research interests are with host/pathogen interactions and gene regulation of Bacillus anthracis, Vibrio cholerae and Salmonella species, particularly as it relates to vaccine, diagnostic and therapeutic development.

Current Projects:

Utilizing proteomic techniques to study immune responses during anthrax, cholera and typhoid.

Gene expression analysis of a large family of Bacillus anthracis genes containing transcriptional elements suggesting induced expression in response to specific amino acid limitation.

Representative Publications:

Ashford, D. et al. (2008). "Application of In Vivo Induced Antigen Technology (IVIAT) to Bacillus anthracis." PLOS ONE, 3(3), e1824. doi: 10.1371/journal.pone.0001824

Calderwood, S.B. et al. (2005). "In vivo induced antigen technology (IVIAT)." Cellular Microbiology, 7(1), pp. 1-9. doi: 10.1111/j.1462-5822.2004.00477.x

Denholm, E.M. & Rollins, S.M. (1993). "Alveolar macrophage secretion of a 92-kDa gelatinase in response to bleomycin." American Journal of Physiology, 265(6 Pt 1), pp. L581-L585. doi: 10.1152/ajplung.1993.265.6.L581

Denholm, E.M. & Rollins, S.M. (1993). "Expression and secretion of transforming growth factor-beta by bleomycin-stimulated rat alveolar macrophages." American Journal of Physiology, 264(1 Pt 1), pp. L36-L42. doi: 10.1152/ajplung.1993.264.1.L36

Festa, F. et al. (2013). "In Press. Robust microarray production of freshly expressed proteins in a human milieu." Proteomics Clinical Applications, 7(5-6), pp. 372-377. doi: 10.1002/prca.201200063

Grundy, F.J. et al. (1997). "Analysis of cis-acting sequence and structural elements required for antitermination of the Bacillus subtilis tyrS gene." Molecular Microbiology, 25(2), pp. 411-421. doi: 10.1046/j.1365-2958.1997.4851839.x

Grundy, F.J. et al. (1994). "Interaction between the acceptor end of tRNA and the T box stimulates antitermination in the Bacillus subtilis tyrS gene: a new role for the discriminator base." Journal of Bacteriology, 176(15), pp. 4518-4526. doi: 10.1128/jb.176.15.4518-4526.1994

Rollins, S.E. et al. (2003). "Yersinia pestis and the plague." American Journal of Clinical Pathology, 119(Supplement), pp. 78-85. doi: 10.1309/DQM9-3R8Q-NQWB-FYU8

Rollins, S.M. & Schuch, R. (2010). "Crowd control: Bacillus anthracis and quorum sensing." Virulence, 1(2), pp. 57-59. doi: 10.4161/viru.1.2.11051

Professional Affiliations:

MGH - Massachusetts General Hospital (Assistant of Microbiology)
MCPHS - Massachusetts College of Pharmacy and Health Sciences (Adjunct Instructor of Biology)
ASM - American Society of Microbiology