Sean Rollins, Ph.D., Biology and Chemistry | Fitchburg State University
Skip to main content

Fitchburg State uses technology to gather information and better understand visitors’ experiences. By continuing to use this website, you consent to this usage in accordance with our Privacy Policy.

Faculty Directory » Sean Rollins


Office Hours:

Semester: Spring 2020
Tuesday and Thursday 8:00am - 9:20am in SCI 110

Office Information:

Room Number: Antonucci Science Complex 237
Phone: 978.665.3915

Courses Taught:

General Microbiology (BIOL 3900)
Survey of Microorganisms
General Biology I (BIOL 1800)


Post-Doctoral Fellowship, Harvard Institute of Proteomics, Harvard Medical School (Biological Chemistry and Molecular Pharmacology)
Post-Doctoral Fellowship, Massachusetts General Hospital, Harvard Medical School (Infectious Diseases)
Ph.D., Ohio State University (Microbiology)
B.S., Rensselaer Polytechnic Institute (Biology)

Research Interests:

My primary research interests are with host/pathogen interactions and gene regulation of Bacillus anthracis, Vibrio cholerae and Salmonella species, particularly as it relates to vaccine, diagnostic and therapeutic development.

Current Projects:

Utilizing proteomic techniques to study immune responses during anthrax, cholera and typhoid.

Gene expression analysis of a large family of Bacillus anthracis genes containing transcriptional elements suggesting induced expression in response to specific amino acid limitation.

Representative Publications:

Ashford, D. et al. (2008). "Application of In Vivo Induced Antigen Technology (IVIAT) to Bacillus anthracis." PLOS ONE, 3(3), e1824. doi: 10.1371/journal.pone.0001824

Calderwood, S.B. et al. (2005). "In vivo induced antigen technology (IVIAT)." Cellular Microbiology, 7(1), pp. 1-9. doi: 10.1111/j.1462-5822.2004.00477.x

Denholm, E.M. & Rollins, S.M. (1993). "Alveolar macrophage secretion of a 92-kDa gelatinase in response to bleomycin." American Journal of Physiology, 265(6 Pt 1), pp. L581-L585. doi: 10.1152/ajplung.1993.265.6.L581

Denholm, E.M. & Rollins, S.M. (1993). "Expression and secretion of transforming growth factor-beta by bleomycin-stimulated rat alveolar macrophages." American Journal of Physiology, 264(1 Pt 1), pp. L36-L42. doi: 10.1152/ajplung.1993.264.1.L36

Festa, F. et al. (2013). "In Press. Robust microarray production of freshly expressed proteins in a human milieu." Proteomics Clinical Applications, 7(5-6), pp. 372-377. doi: 10.1002/prca.201200063

Grundy, F.J. et al. (1997). "Analysis of cis-acting sequence and structural elements required for antitermination of the Bacillus subtilis tyrS gene." Molecular Microbiology, 25(2), pp. 411-421. doi: 10.1046/j.1365-2958.1997.4851839.x

Grundy, F.J. et al. (1994). "Interaction between the acceptor end of tRNA and the T box stimulates antitermination in the Bacillus subtilis tyrS gene: a new role for the discriminator base." Journal of Bacteriology, 176(15), pp. 4518-4526. doi: 10.1128/jb.176.15.4518-4526.1994

Rollins, S.E. et al. (2003). "Yersinia pestis and the plague." American Journal of Clinical Pathology, 119(Supplement), pp. 78-85. doi: 10.1309/DQM9-3R8Q-NQWB-FYU8

Rollins, S.M. & Schuch, R. (2010). "Crowd control: Bacillus anthracis and quorum sensing." Virulence, 1(2), pp. 57-59. doi: 10.4161/viru.1.2.11051

Professional Affiliations:

MGH - Massachusetts General Hospital (Assistant of Microbiology)
MCPHS - Massachusetts College of Pharmacy and Health Sciences (Adjunct Instructor of Biology)
ASM - American Society of Microbiology