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Faculty Directory » Ronald Krieser


Office Hours:

Semester: Spring 2019
Monday 9:30AM - 11:00AM
Thursday 11:00AM - 12:30PM

Office Information:

Room Number: Antonucci Science Complex 338
Phone: 978-665-3619

Courses Taught:

General Biology I (BIOL 1800)
Life Science II
Genetics Lecture and Laboratory
Molecular Biology (BIOL 4500)
Biochemistry (BIOL 3450)
Genetics of Disease


Postdoctoral work, Massachusetts General Hospital/Harvard Medical School, Dartmouth Medical School.
Ph.D. Pharmacology and Toxicology, Dartmouth College
B.A. Biochemistry and Molecular Biology, Clark University

Research Interests:

I am interested in understanding the genetic control of apoptosis, a form of cell death during development and disease. I use the model organism Drosophila to study apoptosis and the disposal of the cell corpse in whole organism and tissue culture systems.

Representative Publications:

Thomenius, M., Freel, C., Horn, S., Krieser, R., Abdelwahid, E., Cannon, R., Balasundaram, S., White, K., and Kornbluth, S. Regulation of programmed cell death in Drosophila by mitofusins. Submitted 2010.

Krieser, Ronald and K. White. Inside an enigma: do mitochondria contribute to cell death in Drosophila? Apoptosis Journal,14:961-968, 2009.

Abdelwahid, Eltyeb, T. Yokokura, R.J. Krieser, S. Balasunduram, W.H. Fowle, and K. White. Mitochondrial disruption in Drosophila apoptosis. Developmental Cell, 12:793-806, 2007.

Krieser, R.J., F.E. Morre, D. Dresnek, B.J. Pellock, R. Patel, A Huang, C. Brachmann, and K White. The Drosophila homolog of the putative phosphatidylserine receptor functions to inhibit apoptosis during development. Development, 134: 2407-2414, 2007.

Pinto-Gonzales Howell, D., R.J. Krieser, A. Eastman, M.A. Barry. Lysosomal DNase II as a barrier to transfection. Molecular Therapy, 8:957-963, 2003.

MacLea, K.S., R.J. Krieser, A. Eastman. Structural requirements of human Deoxyribonuclease II a for formation of the active enzyme: the role of the signal peptide, N-glycosylation, and disulfide bridging. Biochemical Journal, 371: 867-76, 2003.

MacLea, K.S., R.J. Krieser, A Eastman. A family history of Deoxyribonuclease II: surprises from Trichinella spiralis and Burkholderia pseudomallei. Gene, 305: 1-12, 2003.

Krieser, R.J., K. White. Engulfment Mechanisms of apoptotic cells. Current Opinion in Cell Biology, 14: 734-738, 2002.

Krieser, R.J., K.S. MacLea, D.S. Longnecker, J.L. Fields, S. Fiering, A Eastman. Deoxyribonuclease II alpha. Biochemical and Biophysical Research Communication, 292: 415-421, 2002.

Krieser, R.J., K.S. MacLea, J.P. Park, A. Eastman. The cloning of genomic structure, localization, and expression of human deoxyribonuclease IIB. Gene, 269: 205-216, 2001.

Krieser, R.J., A Eastman. Deoxyribonuclease II: structure and chromosomal localization of the murine gene, and comparison to the genomic structure of the human and three C. elegans homologs. Gene, 252: 155-162, 2000.

Krieser, R.J., A Eastman. Cleavage and nuclear translocation of the caspase 3 substrate Rho-GDP dissociation inhibitor D4-GDI during apoptosis. Cell Death and Differentiation, 6: 412-419, 1999.

Krieser, R.J., Eastman, A. The cloning and expression of human deoxyribonuclease II: A possible role in apoptosis. Journal of biological Chemistry, 273: 30909-30914, 1998.