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Faculty Directory » Lisa Grimm


Office Hours:

Semester: Spring 2019
Wednesday 10:00AM - 11:30AM
Thursday 11:00AM - 12:30PM

Office Information:

Room Number: SCI-231
Phone: 978-665-3334

Courses Taught:

General Biology I and II (BIOL 1800, BIOL 1900)
Immunology (BIOL 4810)
Methods in Teaching Science (BIOL 4850)


Postdoctoral work, Massachusetts General Hospital/Harvard Medical School
Ph.D., Molecular and Cellular Biology, University of Massachusetts Amherst
B.S., Zoology, University of Washington Seattle

Research Interests:

Developmental cell signaling pathways
K-12 STEM education
Assessment of student learning in the science classroom

Representative Publications:

Lake, R.J., Grimm, L.M., Veraksa, A., Banos, A., and S. Artavanis-Tsakonas (2009) In vivo analysis of the Notch receptor S1 cleavage. PLOS ONE 4(8): e 6728.

Grimm, L.M., Osborne, B.A. (2001) The role of the proteasome in apoptosis. In: Proteasomes: The World of Regulatory Proteolysis. W. Hilt and H.W. Dieter, editors, LANDES Bioscience, Georgetown, Texas.

Rand, M.D., Grimm, L.M., Artavanis-Tsakonas, S., Patriub, V., Blacklow, S.C., Sklar, J., and J.C. Aster (2000) Calcium depletion dissociates and activates heterodimeric notch receptors. MCB 20: 1825-1835.

Grimm, L.M., Osborne, B.A. (1999) Apoptosis and the proteasome. In Apoptosis: Biology and Mechanisms. S. Kumar, editor, Springer-Verlag, Heidelberg, Germany.

Grimm, L.M., Goldberg, A.L., Poirer, G.G., Schwartz, L.M., and B.A. Osborne (1996) Proteasomes play an essential role in thymocyte apoptosis. EMBO Journal 15: 3835-3844.

Osborne, B.A., Smith, S.W., McLaughlin, K.A., Grimm, L.M., Morgan, G.M., and Goldsby, R.A. (1996) Genetic regulation of apoptosis in the mouse thymus. In Advances in Experimental Medicine and Biology. S. Gupta and J.J. Cohen, editors, pp. 199-207, Plenum Press, New York, NY.

Osborne, B.A., Smith, S.W., McLaughlin, K.A., Grimm, L.M., Kallinch, T., Liu, Z-G., and L.M. Schwartz (1996) Genes that regulate apoptosis in mouse thymus. Journal of Cellular Biochemistry 60: 18-22.

Osborne, B.A., Smith, S.W., Liu, Z-G., McLaughlin, K.A., Grimm, L.M., and Schwartz, L.M. (1994) Identification of genes induced during apoptosis in T lymphocytes. Immunological Reviews 141: 301-320.

Professional Affiliations:

National Science Teachers Association