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Faculty Directory » Sean Rollins


Office Hours:

Semester: Fall, 2017
Tuesdays and Thursdays 8:00 - 9:15 - Antonucci Science Complex 110

Office Information:

Room Number: Antonucci Science Complex 237
Phone: 978-665-3915

Courses Taught:

General Microbiology (BIOL 3900)
Survey of Microorganisms
General Biology I (BIOL 1800)


Post-Doctoral Fellowship, Biological Chemistry and Molecular Pharmacology, Harvard Institute of Proteomics, Harvard Medical School, Boston, MA
Post-Doctoral Fellowship, Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Ph.D. Microbiology, The Ohio State University, Columbus, OH
B.S. Biology, Rensselaer Polytechnic Institute, Troy, NY

Research Interests:

My primary research interests are with host/pathogen interactions and gene regulation of Bacillus anthracis, Vibrio cholerae and Salmonella species, particularly as it relates to vaccine, diagnostic and therapeutic development.

Current Projects:

Utilizing proteomic techniques to study immune responses during anthrax, cholera and typhoid.

Gene expression analysis of a large family of Bacillus anthracis genes containing transcriptional elements suggesting induced expression in response to specific amino acid limitation.

Representative Publications:

Festa, F, S.M. Rollins, K. Vattem, M. Hathaway, P. Lorenz, E.A. Mendoza, X. Yu, J. Qiu, G. Kilmer, P. Jensen, B. Webb, E.T. Ryan and J. Labaer. In Press. Robust microarray production of freshly expressed proteins in a human milieu. Proteomics Clinical Appl.

Rollins, S.M. and R. Schuch. 2010. Crowd control: Bacillus anthracis and quorum sensing. Virulence 1:2:57-59.

Rollins, S.M., A. Peppercorn, J.S. Young, M. Drysdale, A. Baresch, M.V. Bikowski, D. Ashford, C.P. Quinn, J.D. Hillman, M. Handfield, C.R. Lyons, T.M. Koehler, S.B. Calderwood, E.T. Ryan. 2008. Application of In Vivo Induced Antigen Technology (IVIAT) to Bacillus anthracis. PLOS ONE 3:e1824.

Rollins, S.M., A. Peppercorn, L. Hang, J.D. Hillman, S.B. Calderwood, M. Handfield and E.T. Ryan. 2005. In vivo induced antigen technology (IVIAT). Cell Microbiol.

Rollins, S.E., S.M. Rollins and E.T. Ryan. 2003. Yersinia pestis and the plague. Am. J. Clinical Pathol. 119:(Supplement1) S1-S8.

Rollins, S.M., F.J. Grundy, and T.M. Henkin. 1997. Analysis of cis-acting sequence and structural elements required for antitermination of the Bacillus subtilis tyrS gene. Mol. Microbiol. 25:411-421.

Grundy, F.J., S.M. Rollins, and T.M. Henkin. 1994. Interaction between the acceptor end of tRNA and the T box stimulates antitermination in the Bacillus subtilis tyrS gene: a new role for the discriminator base. J. Bacteriol. 176:4518-4526.

Denholm, E.M., and S.M. Rollins. 1993. Expression and secretion of transforming growth factor-beta by bleomycin-stimulated rat alveolar macrophages. Am. J. Physiol. 264(1 Pt 1):L36-L42.

Denholm, E.M., and S.M. Rollins. 1993. Alveolar macrophage secretion of a 92-kDa gelatinase in response to bleomycin. Am. J. Physiol. 265(6 Pt 1):L581-L585.

Professional Affiliations:

Assistant of Microbiology, Massachusetts General Hospital

Adjunct Instructor of Biology, Massachusetts College of Pharmacy and Health Sciences

American Society of Microbiology